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September 18–19, 2026 | Cleveland, OH

Two Days. Thousands of Miles. Countless Whys. One Shared Mission.

Together, we are VeloSano.
Together, to cure cancer.

Register Today

For everyone who wants to end cancer, VeloSano is Cleveland Clinic’s global fundraising movement powering the treatments of today and accelerating the cures of tomorrow through groundbreaking research.

Bike to Cure is where that mission to cure cancer comes to life in Northeast Ohio.  Born from VeloSano’s very first spark, Bike to Cure remains the heartbeat of the VeloSano movement.  Cyclists of all levels, from neighborhood sidewalk riders to seasoned pros, come together as an unstoppable community, turning personal effort into collective progress in the fight against cancer..  And because 100% of every participant-raised dollar directly funds cancer research, every mile and every effort truly matters.

“Bike to Cure is an incredible experience. The excitement, the connection, the purpose – you feel it from kick off to the final mile. We all know someone who has faced cancer, and raising the dollars to fuel the research is the only way we deliver better futures.”

Allison Winter, MD

VeloSano Medical Director

A route for you. And you. And you.

Guardians City Loop

A flat, urban ride that’s perfect for everyone and every bike.

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12-Mile Ride

A ride that extends the Guardians City Loop urban ride further west.

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25-Mile Ride

A mostly flat ride perfect for the casual rider.

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50-Mile Ride

Challenge yourself with this fun 50-Mile course!

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75-Mile Ride

Want to ride more than 50 miles but not quite ready to tackle the 100-mile?

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100-Mile Ride

Tackle a challenging century through Cleveland’s East side!

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100% for the Cure Starts with You!

One person can spark change. One dollar can move research forward. One idea can lead to a breakthrough. Be that one. Let 100% for the Cure start with you.

Register today and take that first step toward the cure.

Your Impact

Every dollar your raise is hard at work accelerating research, new discoveries and treatments. Stay updated on the latest news and stories from our VeloSano researchers, communities and supporters on our Impact Site.

Your Dollars at Work

Reach the Your Full Impact

Your fundraising commitment is just the starting line. Our Fundraising Guide walks you through simple, step-by-step ways to reach your goal and power the impact you want to see.

Start Fundraising

Want to Learn More Before You Bike to Cure?

Register for one of our upcoming virtual information sessions to hear more about VeloSano’s mission to fuel cancer research and how you can pedal progress forward by joining Bike to Cure.

Learn More and Register

Deciding How to Get Involved

Explore our Fast Facts for a quick breakdown of routes, fundraising commitments, and key registration details to help you decide which ride is right for you.

Explore Now

Tune-Up Times

Drop into our open virtual office hours the last Thursday of every month, starting on March 26, where our team is available to answer questions, share ideas and help you build momentum. Need more dedicated support? Email us to schedule one-on-one team with our team.

Email Us

Every Dollar Brings Us Closer to the Cure

Your gift is more than a donation. It’s an investment in our future, a promise of hope for our patients and the fuel that drives research and breakthroughs forward.

Donate Now

Every Mile Matters. Join the Ride.

100% of every participant-raised dollar directly funds cancer research.

Register Today

9500 Euclid Avenue, HS1-15

Cleveland, OH 44195

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